The San Francisco 49ers have struggled to get Deebo Samuel going, and one NFL analyst thinks they may not be able to.

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

The San Francisco 49ers’ playoff chances aren’t completely erased, but they’re low enough that looking toward next year’s ...

There's even a chance Guerendo, who pulled his hamstring on the first day of training camp and missed the first two preseason ...

Kyle Shanahan can no longer save the San Francisco 49ers. We have reached the month of December and quite the time in the NFL ...

The 49ers brass — Kyle Shanahan, John Lynch, and CEO Jed York chief among them — have not wavered on their commitment to ...

East Rutherford, NJ — November 24, 2024 — Malik Nabers of the Giants on the bench late in the fourth quarter as the Tampa Bay ...

Before the 2024 NFL season, Sunday night's Week 13 matchup between the Buffalo Bills and San Francisco 49ers might've been ...

Williams’ wife, Sondra, announced on Instagram on Sunday, Dec. 1 that their son Trenton O'Brien Williams Jr. was stillborn on ...

How to watch Sunday's Bears and 49ers game with betting trends and radio information as Caleb Williams and Co. try to win ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...