Former Wisconsin Badgers running back Isaac Guerendo is in line to serve as the San Francisco 49ers starting running back for ...

San Francisco 49ers defensive end Nick Bosa (hip/oblique) missed his second contest in a row due to hip and oblique injuries.

There's even a chance Guerendo, who pulled his hamstring on the first day of training camp and missed the first two preseason ...

San Francisco 49ers coach Kyle Shanahan is sharing an update on Trent Williams and his family after the left tackle's son was ...

The San Francisco 49ers are a gigantic mess. Nothing looks right on offense. Injuries have decimated both sides of the ball.

Sunday night as snow fell throughout Buffalo’s Week 13 home game against San Francisco. For the Bills, the conditions were ...

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

Sondra Williams, the wife of San Francisco 49ers tackle Trent Williams, said on social media that their son, Trenton, was ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian ...

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...

Just about this time of the year it seems the University of Washington football team takes something away from Steve ...

After Trent Williams and wife Sondra shared the devastating loss of their son Trenton O'Brien Williams Jr. from a stillbirth, ...