The Buffalo Bills were impressive in their week 13 destruction of a desperate and depleted San Francisco 49ers team, blowing ...

Niners coach Kyle Shanahan uses 21 personnel (two backs, one tight end, two wideouts) on a league-high 37.9% of snaps, ...

The Buffalo Bills and San Francisco 49ers clashed in Week 13 contest to continue their respective 2024 NFL seasons. The Bills ...

Micah Roberts, on a 25-6 run on San Francisco 49ers picks, has revealed his Sunday Night Football expert picks for San ...

The Bills (10-2) took a 35-10 win over the Niners (5-7). In what ended up as a winter wonderland in western New York, Buffalo ...

In this week’s game preview, J.B. Long details how much the Los Angeles Rams could lean on wide receivers Cooper Kupp & Puka Nacua, breaks down how dangerous this San Francisco 49ers team can be even ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

ORCHARD PARK, N.Y. (WROC) — In wintry conditions at Highmark Stadium, the Bills took down the 49ers 35-10 to win their fifth ...

San Francisco 49ers linebacker De'Vondre Campbell threatened Bills receiver Mack Hollins for pulling on his dreadlocks during ...

San Francisco 49ers QB Brock Purdy (shoulder) is questionable to play in Sunday night's showdown against the Buffalo Bills, ...

Lake-effect snow has been hitting Buffalo throughout the holiday weekend with is expected to continue off and on through ...

Christian McCaffrey slid down on a run without contact and was ruled out of the San Francisco 49ers’ game on Sunday night ...