Up next for the Bills is the 12-1 Detroit Lions at Ford Field, and if the defense gave up 44 points to the Rams offense, Sean McDermott will need to tighten things up drastically to try and curtail Ben Johnson's high-octane Lions offense that is the highest-scoring unit in football, averaging 32.1 points a game.

Still, the team listed their daily injury report, and a new player popped up – safety Damar Hamlin. Hamlin, along with Taylor Rapp, both “did not practice,” which could force two backup players into the starting safety roles against one of, if not the best offense in the NFL. Cornerback Rasul Douglas was also out on Thursday.

Detroit has won 11 straight games, but the Bills are coming off a loss to the Los Angeles Rams, and using their most recent game as a reality check.