Creature Commandos will reference events in The Suicide Squad, but that doesn't mean they exist in the same continuity. James Gunn asserts the latter isn't DCU canon despite its adopted characters and stories.

James Gunn, one of the CEOs of DC Studios, said in a recent interview that viewers won’t need to watch every single DC project to follow along. He explained that while the productions are part of a connected universe,

"One of the things I've gotten a little sick of is all these stories being relatively the same," said James Gunn, in regard to the superhero genre.