RB Christian McCaffrey, playing in just his fourth game since returning from Achilles tendinitis, suffered a PCL injury ...

The 49ers just lost their second game in a row by at least 25 points for the first time since Jim Tomsula was the head coach.

The San Francisco 49ers’ dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

The San Francisco 49ers had championship aspirations coming into the 2024 NFL season after an overtime loss to the Kansas ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters during a conference call on Monday, the day after the ...

The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

The 49ers running back, the reigning NFL offensive player of the year, is facing a six-week recovery for a knee injury.

Former NFL wideout Ed McCaffrey said it was a tough night after his son, 49ers running back Christian McCaffrey suffered a ...

See what Kyle Shanahan, Brock Purdy, Sean McDermott and Josh Allen had to say following the Week 13 primetime contest.

Rather than viewing this team as one of the class organizations of the NFC, we now need to ponder whether injuries, age, and ...

The San Francisco 49ers endured another disheartening loss Sunday night, falling to the Buffalo Bills and dropping to 5-7 on ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...