Christian McCaffrey's injury against the Bills could be due to the heavy workload he received since returning to the 49ers.

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...

The San Francisco 49ers on Tuesday announced how they’d replace running back Christian McCaffrey. In a slew of roster moves ...

The San Francisco 49ers placed running back Christian McCaffrey on injured reserve Tuesday a day after coach Kyle Shanahan ...

The San Francisco 49ers have signed a former New York Jets running back to replace the injured Christian McCaffrey and Jordan ...

The San Francisco 49ers and fantasy football players who were relying on the NFC West team's running backs are probably all ...

The San Francisco 49ers unfortunately may be without the services of a superstar for the remainder of the season. San ...

Let's take a look back at how the previous Madden cover stars have fared to see if the 49ers star RB has anything to fear ...

Achilles tendinitis robbed San Francisco 49ers star Christian McCaffrey of the first eight games of the 2024 NFL season. A ...

San Francisco 49ers star running back Christian McCaffrey is out for the rest of 2024 after suffering a significant knee ...

The Detroit Lions won't face Christian McCaffrey in Week 17 this season. The San Francisco 49ers running back injured the PCL ...

The 49ers running back, the reigning NFL offensive player of the year, is facing a six-week recovery for a knee injury.