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Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. We thank Dr. Shibani S. Mukerji for review of the case presentation and Dr. Edward T.

More detailed information is provided in Table S1 in the Supplementary Appendix, available with the full text of this article at NEJM.org ... restrictive lung disease, asthma, dental caries ...

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