How M. tuberculosis alters host cell death mechanisms to facilitate infection
Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including ...
EurekAlert!16d
AI accelerates the search for new tuberculosis drug targets
These dramatic changes in bacterial cell structure form consistent patterns that can ... a professor in the Department of Molecular Biology. “Tuberculosis images are inherently difficult to interpret ...
Bacterial species study challenges assumption that structural similarity predicts protein behavior
A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...
Nature8y
A model to predict anti-tuberculosis activity: value proposition for marine microorganisms
The development of new antibiotics effective against all strains of tuberculosis (TB ... we analyzed and compared the physico-chemical properties of 39 current TB drugs and candidates against ...
News Medical on MSN13d
AI-based technology accelerates discovery of new tuberculosis drug candidates
Tuberculosis is a serious global health threat that infected more than 10 million people in 2022. Spread through the air and into the lungs, the pathogen that causes "TB" can lead to chronic cough, ...
EurekAlert!14d
New study uncovers key differences in allosteric regulation of cAMP receptor proteins in bacteria
A new study led by Dr. Rodrigo Maillard at Georgetown University, “Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein through Structural Homology,” published in ...
News Medical11d
Study reveals differences in allosteric behavior of cAMP receptor proteins in M. tuberculosis
A new study, "Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein" published in Biochemistry, provides key insights into how bacterial cAMP receptor proteins (CRPs) ...