Is Isaac Guerendo playing on "Thursday Night Football" or is he out? Is Isaac Guerendo injured or healthy for Week 15 TNF?

NFL insider Ian Rapoport reports that the San Francisco 49ers plan to activate linebacker Dre Greenlaw from the physically ...

Can a trip to the desert snap Kirk Cousins (four games without a TD pass) out of his scoring drought? I think so.

As the San Francisco 49ers prepare for their Thursday night NFC West showdown against the Los Angeles Rams, there remains ...

A quick look at the unparalleled growth of Josh Allen, Bill Belichick's chilling reality and the Rams-49ers game tonight.

With a win on Thursday Night Football, the Los Angeles Rams path to the playoffs will be one step closer. The Rams will play against the 49ers tonight. The matc ...

Week 15 Sam LaPorta hopes his improved statlines culminate in a spiked week, Mark Andrews prepares to rock the seam in New ...

It may look sunny and dry around the Bay Area, but come Wednesday night, rain will make its return. It will be a Level 1 ...

Purdy's numbers have dropped off amid a disappointing season for the 49ers. Is he still in line for a massive contract ...

In a rematch of a wild Week 3 game at SoFi Stadium, the Los Angeles Rams and San Francisco 49ers will renew their rivalry tonight at Levi’s Stadium in Santa Clara. It’s a potential season-altering ...

San Francisco 49ers rookie running back Isaac Guerendo is dealing with a foot injury and is listed as questionable for Week 15 against the Los Angeles Rams on T ...

ET, two of the top offensive performers in the NFL will be on display when George Kittle and the San Francisco 49ers host ...