The San Francisco 49ers will host the Los Angeles Rams at Levi's Stadium in Santa Clara, California, on Thursday, December 12, with kickoff set for 5:15 p.m. PT. The 49ers enter the NFC West clash as 2.5-point favorites. As part of the weekly NFL Pick 'em contest, 49ers...

Micah Roberts, on a 25-6 run on San Francisco 49ers picks, has revealed his Sunday Night Football expert picks for San Francisco vs. Buffalo

The Rams need a win to keep pace in the playoff race, while a win for the Niners would pull them even with LA.

Our writers and editors pick winners in all 16 games, including Lions-Bills, Eagles-Steelers and Seahawks-Packers.

Another 3-2 against-the-spread week for us on our top five picks. Backing the Tennessee Titans was clearly a poor decision, but we knew the hook would come in handy with the Green Bay Packers at +3.5 vs.

Matt Bove and Dom Tibbetts preview Sunday's game between the Buffalo Bills and Detroit Lions. The playoffs are likely here in your fantasy football league. If you're facing tough lineup decisions, we've got 10 RBs to start or sit in Week 15.

Mike Florio discusses why the 49ers are playing with a lot of desperation on TNF against the Rams, which could give them an edge, but Chris Simms questions if San Francisco can get pressure on L.A. without blitzing.

Matt Lutovsky joins the show to break down the Bills vs. Lions game, with its high 54.5-point total, signaling a likely scoring frenzy in this matchup.