Few receivers are better in open space than Khalil Shakir, and he should exploit a depleted Lions defense on Sunday.

The 49ers will not be able to win the NFC West on Thursday night, but they can remain alive in the race for another week. The ...

Detroit Lions prepare for high-stakes matchup against AFC East leaders Buffalo Bills as both teams eye playoff advancement in ...

These current Bills, winners of seven of their last eight games, have been one of the best teams in the NFL all season long. They handed the two-time reigning Super Bowl champion Kansas City Chiefs ...

It's not particularly surprising, but Chubb's efficiency has been abysmal in his return from a season-ending knee injury in ...

Only two games separate the four teams in the NFC West standings. The Seattle Seahawks are on top at 8-6, followed by the Los ...

Jayden Daniels and Caleb Williams are among UPI senior sports writer Alex Butler's five must-start fantasy football ...

However, the moniker actually fits this Week 15 showdown in Motown between the 10-3 Buffalo Bills and the 12-1 Detroit Lions.

The Rams and 49ers are set to face off in a rematch of Los Angeles’ wild 27-24 Week 3 win at SoFi Stadium. During their first matchup, both teams were looking to rewrite their early-season narratives ...

Another 3-2 against-the-spread week for us on our top five picks. Backing the Tennessee Titans was clearly a poor decision, ...

The Buccaneers will take on star quarterback Justin Herbert and an aggressive Los Angeles defense that is allowing the fewest points in the NFL when they visit the West Coast this weekend ...

Both teams are coming in off wins, meaning that both sides will be thinking that maybe—just maybe—they can make a late ...