Real Madrid has confirmed a second injury to a first team star which will likewise severely affect planning for a Champions League showdown with Manchester City.

Elsewhere among the eight ties, Celtic meet Bayern Munich and there is an all-French contest between minnows Brest and serial domestic champions Paris Saint-Germain. The first legs of the play-off matches will take place on February 11 and 12, with the returns a week later.

Friday's draw on CBS Sports Golazo Network detailed the start to the path to the Champions League final at Munich's Allianz Arena on May 31, resolving the next round of matchuops though team's ultimate paths remain unsettled. Teams ranked ninth through 16th at the end of the league phase were seeded and drawn against one of the unseeded teams.