Analyzing Sunday’s San Francisco 49ers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

Analyzing Sunday’s Houston Texans at Jacksonville Jaguars odds and lines, with expert NFL picks and predictions.

There was a time not too long ago when the Jaguars and Texans were seen as the future powers of the AFC South. The Houston Texans (7-5) have held up their end of the bargain. The Jacksonville Jaguars ...

It may be difficult to put much stock in the Bills as a Super Bowl contender, seeing as though this season has played out ...

There have been an incredible amount of great stories across the league, and despite numerous injuries to stars this season, ...

According to 506 Sports’ television coverage map for Week 13, a majority of the country will be watching the Steelers take on ...

On this episode of "Broncos in 60," Head Coach Sean Payton speaks on keeping a routine as the team prepares for its Week 13 ...

Houston Texans WR Nico Collins draws most of the attention, and our NFL expert expects Tank Dell to have a big receiving day ...

Freezing conditions are expected at Paycor Stadium on Sunday, and we expect T.J. Watt and the Steelers defense to make life ...

But that’s the NFL; that’s our job. We’ve really got to come back with ... Doug Marrone and Urban Meyer — have seen their ...

The National Weather Service has extended its "lake effect snow warning" in Buffalo through Monday at 7 p.m. ET, with ...

The Buffalo Bills have activated Matt Milano from injured reserve, putting the starting linebacker in position to play Sunday ...