San Francisco 49ers running back Christian McCaffrey was placed on injured reserve for the second time this season after ...

When it comes to quarterbacks, Kyle Shanahan is extremely picky. He often isn't wild about young quarterbacks who have lots of hype. And when he ...

Should Guerendo start as expected Sunday, it will be just his second start as a running back since he was in the fourth grade ...

Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

San Francisco 49ers linebacker Fred Warner recently revealed that he has been playing through a bone fracture in his ankle, ...

San Francisco 49ers DB Deommodore Lenoir is showcasing his support for athletes with Down syndrome through custom-designed ...

Join Packers Head Coach Matt LaFleur and analyst Larry McCarren as they recap the Packers' Week 13 win over Miami and preview ...

San Francisco 49ers defensive end Nick Bosa (hip/oblique) missed his second contest in a row due to hip and oblique injuries.

McCaffrey was initially said to be out at least six weeks — with five weeks left in the season. Niners head coach Kyle ...

The San Francisco 49ers have had a very difficult time but probably even more so their running back Christian McCaffrey. The ...

Christian McCaffrey, the San Francisco 49ers running back and reigning NFL Offensive Player of the Year, will miss the rest ...

The San Francisco 49ers on Wednesday began their week of practice as they gear up for what amounts to a season-ending stretch ...